Updating estimates of the economic costs of alcohol abuse
(125-500 mg orally every morning) is an acetaldehyde dehydrogenase inhibitor that blocks the oxidation of acetaldehyde to acetic acid, resulting in the accumulation of acetaldehyde in the blood and causing an aversive reaction (known as a disulfiram-alcohol reaction): flushing, tachycardia, hyperventilation, and nausea.
Further, it is a syndrome that is substantially underdiagnosed and undertreated. As women age, however, they may be especially at risk for alcohol-related problems, since they become more likely than men to outlive their spouses and face additional losses that may lead to loneliness and depression; they also have a greater physiological risk for alcohol-related health problems as they age. Assessing and monitoring medication therapy in seniors.